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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71008eeb3a176ee0b5302ae813caf6ddbd9803c36b8e7b28b3f952c440756141' 
  AND token = 'Ax6V3DvsLbR5D3wWsSKStEPC3m9r+z4LzChoGZFgI5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}