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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52dd169092ae0205b7c1431ba243ebce6495a1c4e0b4d7f99b086bddc7488fa' 
  AND token = 'UxzNk6fSslxr2IDjx3tK2qSIkmwJTNDUxmsCm4K0jNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}