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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e88c0d9cba590f8dec4904ba4072bee1386df702e4804f01b21a65fd0563ae5' 
  AND token = 'cS1f6AutNVHMjUuC6bBo1SICXBOldWGrRWIIVLYcRVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}