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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea52002b6c21ce911658205ee2d4663bcddc7cc4d9af6c5c623b38dd438e339f' 
  AND token = 'H5XTRis0mpPx5mzljkOX5Lhq5FpIaFYlronUXsRhFaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}