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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95cb683a7c09d031e52d42b2c960f3523fed4383235627bbfa17936db20a81a3' 
  AND token = 'LjjLRY0NmQ7gJRbhqKo7cMEx6fLG3etZhuHPs0XySgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}