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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff2086b15b1dd0a784a5e3f930a5103f482d74438d152280796976ab9820afe' 
  AND token = 'Nq5xvcKSr2KTSfEr7krNpTB+QSrSGUVTtMfAUAkj2+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}