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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e53cc712b904165099683312353956002c774c42f946342e38fc6997d81fa7a' 
  AND token = 'goOT0A1Q2dQMQAoobG+oj11xYg8TiZC7JWCPFlMpWC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}