SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc4ab536867010cdf80abed2e6202461f3ba3a37e0da5e95b6e4617d0c57a14' 
  AND token = '2dIOWBGqxb6xZjGSDcyx2RfixOLhaz9Yns1rTyJJ1kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}