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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2513a7b749e2b2dba1973ddf8d9ddb959435b731740dad13fdb816e5ce96aea5' 
  AND token = 'u6m3DTOx9koqAPq5+vZILVIPKuDEk4s022Z4zxBY7vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}