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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f423c03827388fa8206142a452e230ee0015930a179ab7dd09598cbfa9ac23' 
  AND token = 'Y/heIp5uZjLFaijRzbaaocbvP3gkV6MRSa4kSkZiQnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}