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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52fb52e8b457592e7955b1f1f1bacb5d0c790b45ef771069c18e5660c6042498' 
  AND token = 'FCecFBG2aNERLfr2xO5/0GmXZLH6h4ZkdseyyUD3Rmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}