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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '103e69b7b92c8d9f3033c9f66b80921f97fa08629bf1c16ab3b11f495e62fa25' 
  AND token = 'wdrTSEaMeTPBAHFcCXvLxhC5jVyhN2SOqcRI8kXiN4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}