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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f47316190452bff5682d00666d3f552d30d62751b6892a8283480812e2b9d6' 
  AND token = 'Jrfc8lEae5En486CUVXqaTOHR9cbIEVmRqzY78brNF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}