SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df5ba1f0f544eeac5ebdf6272bd1ae3aa86f35ee044d1f4247d905947063d84' 
  AND token = '2+J5eFMQYfuAXKYi9cW9fPnerfRwqR7OlYlD8RpVIKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}