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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a72de5e35fba0495a97070923a8ac69f04f4b8e9318872ba9f54b7df6897fed' 
  AND token = 'SSLS2vC/3i5HLLkJdyKv3FHHVkpvIo7gc0hCMOC/TW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}