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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3112399edb50da9a2cb08ef208ca39f7220782092e1d61473a7880f3fd9422' 
  AND token = 'czM3JrT+soTigsx6/Tl8WxmcIaNWinxsR0dd2QqsrJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}