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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381cb9e36e64070bbb7aae5baf3cc2cc0ce0c841f6257b400355e78044b452c0' 
  AND token = 'ZwodkNvMIubxQWiFZtpnn3TbjMCj1QA7N7ux9VEhUAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}