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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c424eed4272625a6155e66be0bbff4e0e330063e421472b4de6ad1d2eec6cde' 
  AND token = 'XXUs2ey280t5qEwJQ9u/nsDDudgUSSVpWLzAQFN24KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00216

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}