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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5a1650b43edd82b9e5a0fd43002c7cf6fb3263f4343be9578aa13f15cc09eb' 
  AND token = 'StTG/lqNPlQU9hDITZ0DX2khoCbA/5VwXFWzcd7PS6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}