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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e047ab658ba6d18009a01de114c06750a93f43ab6b74924b0a60a37f8c98e3df' 
  AND token = 'LFMXwlCE3GN4t+oLIvkFOs+YxSj1/EYrpjdvN5fXb94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}