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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f8385a341cabad4724d1eacdffd6c2d30f07a15a35455c11d3883fa8248542' 
  AND token = 'KVAmdEfUl5v9t/f8oo/nrKqWUkqMkwUikC3nEhhQsO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}