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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7514408a3009af1ff318f4ad49710f5016eebd2cd55b9d5257a8902e4c0e27' 
  AND token = 'G1o69a0Bus+4lFfYn6+SaKNmvHyUgRNyyrT3SC1a2YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}