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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c3941d8c3fa9d7fe2302a081541232e3b95ed34fc85dda9af8d5568705e396' 
  AND token = 'wK1Zmh0sbIQ5AkcWmI8WsRfAfMTbQw/+se4egrx7Cqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}