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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2d0a3033f0e976b42e6715e5bbd2144a8bca44628b8a561b13dbfe624aae76' 
  AND token = 'Pg7KDj8TVI6RGVySxzpIBOurbt1LTsY0bxrwUrUUWZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}