SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078d46190aaf177064a7c14441314c330431667b9893d8ac6bd188713273a62c' 
  AND token = 'g4nuoXmUEoU/32h4dp65Evim4vgLHgy5edkErDlkXHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}