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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fa3cac8baa6773b224afd36d972c273b9fb621bb96dd98261594dafd258b8b' 
  AND token = 'pc8RRpYh5fFEEg+HG/CqC3DH2MxQfK0qd7rNwCsf+WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}