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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78545870aed0fae49b62e6c7a7e05b1b8cbb1122ae932b7b1336a1a5f79cecd8' 
  AND token = 'YsRGivpo48iPAQ3EI4Gi8CIMj1wjjo4dIxHf8riB+RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}