SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94ac5284062c3908b70283a371448a61bcbcc75f8d5098803db3f05f12017017' 
  AND token = 'iq8XHeq/jsDpiQD+5+IsfRT8WWdlD8qz+0f9k8R3ycE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}