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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413021afe580a94fd89e961f52f7bd99cca90fc94c0d54425fd94487ef5ce2d2' 
  AND token = '65wkPJf33Iy6jDmNjFLGXmwaVjcFUHQYJP3ma9vp7zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}