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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fa240e6450d541377c6ffa3b4ccd8ba2022e25bad1e48e24cc4af87fc6af2c' 
  AND token = 'AEmkhrlKMKQhv0aPOhMCrh4I8UgiT1MkOkO+R32oOGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}