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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5eeef40f3ac559a46d3029e3cc83c3233fd92b7204753ad2e08b769f78ed882' 
  AND token = 'DKBPYeBpOwiUmRLIkcJP4qLgX5QLF9mI+kh2dRZ3LW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}