SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8407e96800607fac2b9cc647ad00059a0216a1f0c454e292f9322c391bc289' 
  AND token = 'Jtg/VDmg8symTUjCwZQAIXX8d0CKg89zU3P5u3K1xBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}