SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    264156, 264927, 264928, 264929, 264930, 
    264931, 264932, 264933, 264934, 264935, 
    264950, 264951, 264952, 264953, 264954
  ) 
  AND feature_id IN (649, 882) 
  AND lang_code = 'en'

Query time 0.00281

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "13.08"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 30,
      "rows_produced_per_join": 30,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "7.08",
        "eval_cost": "6.00",
        "prefix_cost": "13.08",
        "data_read_per_join": "23K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (264156,264927,264928,264929,264930,264931,264932,264933,264934,264935,264950,264951,264952,264953,264954)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (649,882)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
264156 649 62612
264927 649 62608
264928 649 62609
264929 649 62610
264930 649 62611
264931 649 62608
264932 649 62609
264933 649 62610
264934 649 62611
264935 649 62612
264950 649 62608
264951 649 62609
264952 649 62610
264953 649 62611
264954 649 62612
264156 882 60392
264927 882 60392
264928 882 60392
264929 882 60392
264930 882 60392
264931 882 60401
264932 882 60401
264933 882 60401
264934 882 60401
264935 882 60401
264950 882 60412
264951 882 60412
264952 882 60412
264953 882 60412
264954 882 60412