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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf861dbca5f4ed42780858a037dd6c1e2f504b1240d2facac74ebb572dc78f8' 
  AND token = 'SmN9F0DfXu0MvR+XElmn5MFP7ec86/yLt8ZcDXk8DIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}