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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '555cd8f9c7e8cf552be458298ea818ab52cb68e21f26dd4828b491682d82c4c6' 
  AND token = 'ibk6fSQ9LVT4QTSQ+pvmwl/Xv0ijN8XHAaNl1LJkXLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}