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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f874646581144618b65b0c3bf292c91ed9d9f9c07b0d17cb6f983bad3b08ad67' 
  AND token = 'NZELp3k/bk9yDUtKHDOoepgqwKIQrDpHEUXtQJMAkg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00184

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}