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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424a6d2474f6afd8106361c50e5bba472e1a5b70a83e31af1e58511d6542932b' 
  AND token = 'PIp8eFVbjr5MGJEovFNuiQH3aCBerpzadmutJLXhgbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}