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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122bc3ef1bf3b1252602f05a2cd6092c7aefe1e00aeae6932ba31641f884753e' 
  AND token = 'hdTTe6Ww/CXy5IxPNKTVI/fMpZr8ZpYDg2jIY92NyGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}