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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4329c9b304c316be7359fec94ee49a55fa4386a2a87c8e5eec318b63dd796063' 
  AND token = 'rRULU1+uPWT0dmvZW0Q5nWZTDoKgHLiiL5xYXopuIAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}