SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b211c9f502f0bad8288b02e49f76a7b6c8cbe220883876955d1254ac7fc76e3' 
  AND token = 'p29WGOzqaikaAt19AJWbecBAMmGrmZuL62DTvcR8ABo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}