SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7321a3c71f7d1b27b01c08ea58289460da6474addfc20c2bc56afc1d2574aa5e' 
  AND token = 'Vv0UznEUb3Vq1irqIfr2i7eQvOM7Pyw+TlS84b1mKwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}