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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66e318aa3e6e870b020eece405a77a49b53022d7dc5a5bdd80494d7eb99efee' 
  AND token = 'tL91WS5L4xUamefPt2pFUhLOrwZ+uy8PTaTUS7525Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}