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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91266a50bad8209ebe86081de4bc946479530731b853edc55ca3ab069b3f2af3' 
  AND token = '6sCCqzcL+IURX2cbpK2DWq1tUuCgYXltSlmpXGa4cWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}