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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3ee66f603eb1b6e39f3da251c1c735d0e6189e6206df4bfe6c793e96b199a0' 
  AND token = 'OqeZdp0/PKj/+DJlXBx9oRI870dTVrXi4FZG1OimlNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}