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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3ee085e24129d09f940363050157ee1c4b73e88b10b2f3bf34192848b0bd4a1' 
  AND token = 'kAzfj0udV4pjC2olW3rl5TzA7Qbt8zbLJM6Qzb7GdVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}