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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5606b08186fb82f9ef84996c00f18199867f5a97b0bf7fc4edb7379cca4e3ef3' 
  AND token = 't+GrzvAMso4jbUmr7845ZUIEa4XYTahODTuaWDxgFKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}