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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c2e16ef471d1a98076b3ca6692cae0dfd118e313d79fa70314733e354d666c' 
  AND token = 'j31JGVPE5PuHd5UzS4T7zcYM24qUgEoPd2+VfCCKMkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}