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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cdbb98a6ba5f9050893eb74ba796f0ef9232bd9514d8c7d11d548cb483de8a' 
  AND token = 'raIFX8GDmV87WGEisHp9/HW9Xa23OqsJ1VNyOL7iZvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}