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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad6cfe1b11a0289b8d87f8593ea0d0314307db71f517636b0708d9f13b8e04f' 
  AND token = 'KkcfgddKNos1PUq0vbSs1phykPKldZXx6lgaV22mES8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}