SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (
    432541, 432542, 432543, 432544, 432545, 
    432546, 432547, 432548, 432549, 432550, 
    432551, 432552
  ) 
  AND feature_id IN (860, 1013) 
  AND lang_code = 'en'

Query time 0.00276

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "10.67"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 24,
      "rows_produced_per_join": 24,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "5.87",
        "eval_cost": "4.80",
        "prefix_cost": "10.67",
        "data_read_per_join": "18K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (432541,432542,432543,432544,432545,432546,432547,432548,432549,432550,432551,432552)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (860,1013)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}